A blood smear is a type of blood test. St Louis, MO: Elsevier; 2017, Ⓒ 2021 About, Inc. (Dotdash) — All rights reserved, Lynne Eldrige, MD, is a lung cancer physician, patient advocate, and award-winning author of "Avoiding Cancer One Day at a Time. Unlike automated tests (such as a CBC), a technician or physician looks at a blood smear under the microscope in order to detect a wide range of changes that give clues to underlying diseases. The RBCs are stacked like coins. For a blood smear, the lab professional looks for blood cell problems that may not be seen on a computer analysis. A procedure in which a sample of blood is viewed under a microscope to count different circulating blood cells (red blood cells, white blood cells, platelets, etc.) Test Code A69 Peripheral Blood Smear (PBS); Consult & Report Important Note. This includes finding myeloblasts, metamyelocytes, promyelocytes, myelocytes, or with lymphocytes, finding lymphoblasts or prolymphocytes. Green neutrophilic inclusions in liver disease. Sickle cell anemia is an inherited disorder in which abnormal hemoglobin (the red pigment inside red blood cells) is produced. Toxic granulations (in neutrophils): Seen with severe infections, Hypersegmented neutrophils (more than 5 nuclear lobes): Seen with vitamin B12 and folate deficiency as well as myeloproliferative disorders, Bright green inclusions: Sometimes seen in liver failure and associated with a poor prognosis, Bilobed neutrophils: Seen in some genetic syndromes. 23rd ed. A peripheral blood film is a diagnostic tool that can be used to diagnose and monitor diseases that affect blood cells. Reference ranges exist for the number of red blood cells, white blood cells, and platelets, as well as the expected appearance of these cells. It evaluates the white blood cells (WBCs, leukocytes), red blood cells (RBCs, erythrocytes) and platelets (thrombocytes). A procedure in which a sample of blood is viewed under a microscope to count different circulating blood cells (red blood cells, white blood cells, platelets, etc.) When your sample arrives in the lab, a technologist will carefully prepare the slide. Many disorders such as malaria, anemia, leukemia, thrombocytopenia, sickle cell anemia etc., can be diagnosed by evaluating blood cells. The maturity of white blood cells can give information about the severity of infection or suggest an underlying leukemia. The preparation of the slide requires careful technique, and results may be inaccurate if the slide is too thin or too thick. These cells should be reported as A. Nucleated RBCs B. Blasts Clinical Definition of Peripheral blood smear, Reason to take Peripheral blood smear Test, Preparations Needed for Peripheral blood smear Test, https://medlineplus.gov/labtests/bloodsmear.html, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415389/, https://labtestsonline.org/tests/blood-smear. A complete blood count (CBC) provides the number of: Red blood cell and platelet indices further describe the cells that are present and include. It has a wide range of uses, including distinguishing viral infections from bacterial infections, evaluating anemia, looking for causes of jaundice, and even diagnosing malaria. of collection) Preparation of Blood Film: The slide should be clean. He is an associate professor of clinical medicine at Weill Cornell Medical College and attending physician in the Department of Hematology Oncology at the New York Presbyterian Weill Cornell Medical Center. J Clin Pathol. When a particular type of white blood cells is increased, it can give important clues about underlying problems. Hematopathology Morphologic Evaluation | Test Detail | Quest Diagnostics A band count greater than 15 percent is referred to as a "left shift.". A blood smear involves looking at a sample of blood under the microscope after applying special stains and looking for abnormalities or changes in red blood cells, white blood cells, and platelets. When your doctor orders a blood test, he or she chooses from a list of chemical studies to be performed in a laboratory on your blood sample. Some of these include:. For example, your doctor may … A blood smear involves looking at a sample of blood under the microscope after applying special stains and looking for abnormalities or changes in red blood cells, white blood cells, and platelets. What Is MCV (Mean Corpuscular Volume) on Your Blood Count? Sometimes a diagnosis can be made based on the blood smear alone (such as with hereditary elliptocytosis) and other times further testing will be indicated. Other findings may include hypogranular platelets. A tourniquet is applied to make the vein engorged and more visible, and then the technician will insert the needle into your vein. Other tests that may be done in conjunction with a blood smear include: There are few risks associated with a blood smear, though bleeding could be of more concern for those who have a low platelet count or are on blood thinners. While automated tests are rapid and cost-effective in some settings, we don't have technology that can replace the human eye in distinguishing the many subtle changes in blood cells that give important clues in diagnosis. There is no special preparation prior to having a blood smear drawn, and no eating or activity restrictions are needed. Other immature white blood cells should not be seen on a blood smear (in peripheral blood) and raise suspicion about leukemia. A blood smear is a blood test that provides details about the number and shape of blood cells. Peripheral blood smear examination is usually done on clinical request by the clinician due to suspicion of a blood disorder. *I authorize Portea representative to contact me. Ann Ib Postgrad Med. A blood smear is often done in conjunction with a CBC and indices, and it is the combination of these studies that is most helpful. A blood smear also gives a "second read" to results obtained on the CBC. Eosinophils. Blood smear is These lab tests can provide important clues about what's going on inside your body. to evaluate an infection (identifying the types of white blood cells present can help determine if an infection is viral, bacterial, or, to look for causes of unexplained jaundice, to evaluate symptoms of lightheadedness and palor (paleness), to look for causes of petechiae, bruising, or excess bleeding, to investigate findings suspicious for blood-related cancers. Rouleaux formation (and consequently, having the RBCs becoming stuck in capillaries) is an underlying process behind diabetic retinopathy. A blood smear can also detect parasites in your blood. If a person has received a blood transfusion, the smear will include a combination of native and donated blood cells.. It may vary with age, gender, and other factors. Notify the laboratory of the date and time of the CBC with Differential order that requires smear review by a pathologist. CBC (includes Differential and Platelets) with Smear Review - A complete blood count is used as a screening test for various disease states including anemia, leukemia and inflammatory processes. Blood tests. Thomas, Liji. Peripheral blood smear analysis is a common practice to evaluate health status of a person. It evaluates the white blood cells (WBCs, leukocytes), red blood cells (RBCs, erythrocytes) and platelets (thrombocytes). The blood smear is a simple blood test. A blood smear can also detect parasites in your blood. Some of these include:. There may be a sharp sting when the needle is inserted and some slight pressure as the sample is taken.